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We firstly reported that for equal cumulative exposure, participants exposed to higher concentrations over shorter duration had a higher risk of CVD mortality than those exposed to lower concentration over longer duration

while not everyone who quits smoking will experience depression, research suggests that individuals who have a history of depression or other mental health conditions may be more vulnerable to developing depressive symptoms after quitting smoking

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Thus, we aimed to investigate how cigarette smoking affects body weight, food intake, plasma leptin concentration, hypothalamic NPY peptide, adipose mass and mRNA expression of uncoupling proteins (UCP), and tumor necrosis factor (TNF)